It's fairly simple to configure the mouse. You pick a mouse type from the mouse type menu, and then, if necessary, pick the communications port that the mouse is attached to. After you press the [OK] button to make the changes, the system will attempt to configure the mouse -- if it fails, you'll probably know about it since the mouse will either stop responding or will become uncontrollable.

Mastodon Linux uses the gpm program to control mice, thus the mice this program knows about is restricted to the mice supported by gpm 1.10.